Table 1 Characteristics of the HIV-positive adult study population in Durban, 2013–2017.

From: Validation of clinic-based cryptococcal antigen lateral flow assay screening in HIV-infected adults in South Africa

 

Mean ± SD or N (%) (N = 1,296)

Sociodemographics

Age

33.4 ± 9.1 years

Female

766 (59.1%)

Zulu Ethnicitya

726 (93.8%)

History of HIV and Cryptococcus Testing

Previously tested for HIV

813 (62.7%)

Ever tested Cryptococcus positive

1 (0.1%)

Clinical Symptoms and Examination

Fatigue

608 (47.0%)

Headache for >24 hours

388 (29.9%)

Fever

385 (29.7%)

Loss of appetite

323 (24.9%)

Weakness in legs

217 (16.8%)

Neck stiffness

198 (15.3%)

Weakness in arms

186 (14.4%)

Difficulty walking

177 (13.7%)

Nausea or vomiting

151 (11.7%)

Presence of oral thrush

140 (10.9%)

Blurry or double vision

96 (7.4%)

Confusion

58 (4.5%)

Seizure within last 7 days

13 (1.0%)

CD4 T-cell count

Median [IQR] cells/mm3

306 [168, 475]

<200 cells/mm3

384 (30.5%)

<100 cells/mm3

176 (14.0%)

  1. IQR = interquartile range; SD = standard deviation.
  2. a522 participants did not have ethnicity recorded.
  3. *CrAg LFA tested on 1,163 venous whole blood, 1,164 fingerprick capillary blood, and 1,151 urine specimens.