Figure 1

Effect of MG132 on the urinary protein excretion rate in DN rats. In DN rats, both MG132 and deguelin treatment effectively reduced urinary protein excretion for the indicted time. NC: normal control group; DN: diabetic nephropathy group; MG132: diabetic nephropathy plus MG132 treatment group; Deguelin: diabetic nephropathy plus deguelin treatment group. Means ± SEM; N = 6; *P < 0.05 vs. NC; #P < 0.05 vs. DN.