Figure 2 | Scientific Reports

Figure 2

From: Macrophage Migration Inhibitory Factor Acts as the Potential Target of a Newly Synthesized Compound, 1-(9′-methyl-3′-carbazole)-3, 4-dihydro-β-carboline

Figure 2

Binding analysis between MCDC and recombinant human MIF protein. (A) The predicted interaction between MIF and MCDC. MIF (PDB ID: 3L5S) is presented as a homotrimer (labeled in blue, green, and pink and rendered as ribbons). Binding of MCDC (stick rendering) to Asn6 of one MIF subunit (the pink one) via a predicted hydrogen bond (the yellow dashed line) is shown. The structure was computed by Discovery Studio 3.0. (B) Representative biosensorgram between MCDC and MIF. Affinity binding of MCDC to MIF was measured by real-time surface plasmon resonance (Biacore analysis).

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