Table 1 Species-specific missense mutations of positively selected genes.
From: Comparative genomics sheds light on the predatory lifestyle of accipitrids and owls
Species | Genes | Mutation sites (human) | Amino acids (raptors/human) | Polarity | PolyPhen-2 | |||
|---|---|---|---|---|---|---|---|---|
HumanDiv | HumanVar | |||||||
Accipitrids | XRCC5 | 104 | K(Lys)/Q(Gln) | polar/polar | 0.27 | benign | 0.055 | benign |
163 | I(Ile)/F(Phe) | unpolar/unpolar | 0.89 | possibly damaging | 0.557 | possibly damaging | ||
178 | V(Val)/R(Arg) | unpolar/polar | 0.047 | benign | 0.083 | benign | ||
389 | A(Ala)/M(Met) | unpolar/unpolar | 0.937 | possibly damaging | 0.967 | probably damaging | ||
691 | T(Thr)/A(Ala) | polar/unpolar | 0.919 | possibly damaging | 0.312 | benign | ||
Owls | ALCAM | 259 | I(Ile)/A(Ala) | unpolar/unpolar | 0.617 | possibly damaging | 0.336 | benign |
297 | M(Met)/T(Thr) | unpolar/polar | 0.85 | possibly damaging | 0.557 | possibly damaging | ||
