Table 1 CFT073 induced gene upregulation compared to unstimulated renal fibroblasts.

CXCL10

16858

Homo sapiens chemokine (C-X-C motif) ligand 10

CXCL9

6485

Homo sapiens chemokine (C-X-C motif) ligand 9

CXCL11

3525

Homo sapiens chemokine (C-X-C motif) ligand 11

OASL

2200

Homo sapiens 2′-5′-oligoadenylate synthetase-like

RSAD2

1645

Homo sapiens radical S-adenosyl methionine ___domain containing 2

CCL5

1610

Homo sapiens chemokine (C-C motif) ligand 5

XLOC_l2_000297

1507

BROAD Institute lincRNA (XLOC_l2_000297), lincRNA

CD38

611

Homo sapiens CD38 molecule

GBP4

592

Homo sapiens guanylate binding protein 4

CSF3

587

Homo sapiens colony stimulating factor 3

CCL8

532

Homo sapiens chemokine (C-C motif) ligand

GBP1P1

498

Homo sapiens guanylate binding protein 1, interferon-inducible pseudogene 1

IFIT2

440

Homo sapiens interferon-induced protein with tetratricopeptide repeats 2

CMPK2

439

Homo sapiens cytidine monophosphate (UMP-CMP) kinase 2

SSTR2

384

Homo sapiens somatostatin receptor 2

HERC5

380

Homo sapiens HECT and RLD ___domain containing E3 ubiquitin protein ligase 5

KIF5C

361

Homo sapiens kinesin family member 5C

TNFSF13B

273

Homo sapiens tumor necrosis factor (ligand) superfamily, member 13b

HRASLS2

268

Homo sapiens HRAS-like suppressor 2

IDO1

255

Homo sapiens indoleamine 2,3-dioxygenase 1

NOD2

243

Homo sapiens nucleotide-binding oligomerization ___domain containing 2

C16orf47

242

Homo sapiens chromosome 16 open reading frame 47

GPR84

222

Homo sapiens G protein-coupled receptor 84

GBP5

218

Homo sapiens guanylate binding protein 5

CIITA

211

Homo sapiens class II, major histocompatibility complex, transactivator

OAS1

179

Homo sapiens 2′-5′-oligoadenylate synthetase 1

UBD

175

Homo sapiens ubiquitin D

GCH1

166

Homo sapiens GTP cyclohydrolase 1

CCL20

166

Homo sapiens chemokine (C-C motif) ligand 20

TBC1D1

141

Homo sapiens TBC1 (tre-2/USP6, BUB2, cdc16) ___domain family, member 1