Table 3 Quantitative real-time PCR data for CFT073 compared to unstimulated renal fibroblasts.

From: Human renal fibroblasts are strong immunomobilizers during a urinary tract infection mediated by uropathogenic Escherichia coli

Gene symble

Fold change

Description

IL-1β

75 ± 23a

Interleukin 1, beta

NOD2

350 ± 126

Nucleotide-binding oligomerization ___domain containing 2

CXCL10

17910 ± 1327a

Chemokine (C-X-C motif) ligand 10

CXCL9

18249 ± 5777a

Chemokine (C-X-C motif) ligand 10

PTCH1

−7.9 ± 1.1a

Patched 1

TET1

−3.0 ± 0.4a

Tet methylcytosine dioxygenase 1

PLCB2

−1.6 ± 1.1a

Phospholipase C, beta 2

CPEB1

−9.5 ± 0.3a

Cytoplasmic polyadenylation element binding protein 1

  1. n = 3.
  2. aSignificantly altered genes compared to unstimulated renal fibroblasts.
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