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Figure 1

From: Palladium based nanoparticles for the treatment of advanced melanoma

Figure 1

Formulation of Tris DBA-Pd nanoparticles. (A) Structure of Tris DBA-Pd (mw: 915.72 g/mol). (B) Hyaluronic Acid (HA)-5β-cholanic acid conjugate was synthesized by linking the carboxyl group of HA with the amino group on 5β-cholanic acid in the presence of EDC and NHS. HA nanoparticle/Tris DBA-Pd complex was prepared under high pressure homogenizer to encapsulate the Tris DBA-Pd into a more soluble HANP/drug complex.

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