Figure 6
From: Palladium based nanoparticles for the treatment of advanced melanoma
LM36R xenograft tumors in mice post treatment with HANPs - FGF2 staining. Immunohistochemistry was performed on tissue harvested from mouse tumors to qualitatively assess expression of FGF2. (A) Control with empty HANPs with strong FGF2 staining. (B) Free Tris DBA-Pd group with strong FGF2 staining. (C) HANPs with Tris DBA-Pd and light staining of FGF2 indicating a reduction in FGF2 expression. (D) HANPs with Tris DBA-Pd conjugated with the IGF1R antibody show a light staining of FGF2 indicating a reduction in expression of FGF2.
