Figure 6
From: Molecular architecture of the Jumonji C family histone demethylase KDM5B
(A) Mapping of differences in HDX-MS data between ccKDM5B and KDM5B using a white to red coloring scheme mapped on to a KDM5B 1–820 homology model. Color mapping from no difference in exchange between ccKDM5B and KDM5B colored white to large differences in red. First and last visible residues in the figure are labeled. Domains and substrate access direction are also indicated. (B). Mapping of HDX-MS data to the model of KDM5B 1–1078 using a blue-yellow-red coloring scheme. Regions 1–24 and 196–378 are omitted as no reliable templates are available. Regions where no exchange data is available is colored grey.
