Figure 1 | Scientific Reports

Figure 1

From: Assessment and Clinical Relevance of Serum IL-19 Levels in Psoriasis and Atopic Dermatitis Using a Sensitive and Specific Novel Immunoassay

Figure 1

Baseline IL-19 levels are markedly increased in psoriasis and are highly correlated with PASI scores in psoriasis, genital psoriasis, and psoriatic arthritis patients. (a) The normal donor IL-19 geometric mean was 11 pg/mL, while in psoriasis (PsO) patients at baseline, the IL-19 geometric mean was 87 pg/mL (p < 0.0001). (b) Baseline IL-19 levels were measured in 556 patients with psoriasis (PsO), 120 patients with genital psoriasis (gPsO), and 293 patients with psoriatic arthritis (PsA). IL-19 was highly correlated with PASI (Spearman’s r = 0.64, p < 0.0001). (c) Same as Fig. 1b but restricted to PASI < 10 (Spearman’s r = 0.53, p < 0.0001). (d) Same as Fig. 1b but restricted to PASI < 5 (Spearman’s r = 0.39, p < 0.0001).

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