Table 2 Cox regression models for renal survival via univariate and multivariate analysis.

From: Low serum C3 level, high neutrophil-lymphocyte-ratio, and high platelet-lymphocyte-ratio all predicted poor long-term renal survivals in biopsy-confirmed idiopathic membranous nephropathy

 

Univariate

Multivariable

Hazard ratio

95%CI

P value

Hazard ratio

95%CI

P value

Male

1.29

0.69–2.42

0.428

   

Age

1.04

1.01–1.06

0.002

1.02

0.99–1.05

0.301

Blood urea nitrogen

1.03

1.02–1.03

<0.001

   

Serum creatinine

1.30

1.19–1.41

<0.001

0.91

0.72–1.14

0.408

eGFR

0.97

0.96–0.98

<0.001

0.97

0.95–0.99

0.011

Uric acid

0.95

0.81–1.12

0.549

   

Albumin

0.96

0.61–1.51

0.856

   

Total protein

0.77

0.56–1.07

0.116

   

LDL

1.00

1.00–1.00

0.427

   

Urine PCR

1.06

1.04–1.09

<0.001

1.03

1.00–1.07

0.068

Daily urine protein

1.02

0.99–1.05

0.244

   

IgG

1.00

1.00–1.00

0.541

   

IgA

1.00

0.99–1.00

0.053

   

C3 ≤ 93.4 mg/dl

2.15

1.14–4.02

0.017

0.95

0.46–1.94

0.884

C4

1.02

1.00–1.04

0.084

   

NLR > 3.34

3.30

1.78–6.13

<0.001

2.58

1.04–6.42

0.042

PLR > 14.48

2.54

1.38–4.69

0.003

0.92

0.40–2.09

0.837

Stage 3–4/1–2

2.41

0.78–7.43

0.127

   
  1. Cox proportional hazard regression. *p < 0.05, **p < 0.01.
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