Table 5 Diagnostic group differences in ophthalmological exam and OCT findings.

From: Visual impairment in aging and cognitive decline: experience in a Memory Clinic

 

OR (95% CI)

p

Reduced visual acuity:

     Dementia vs SCD

3.36 (1.77–6.39)

<0.001*

     Dementia vs MCI

1.61 (1.24–2.10)

<0.001*

     SCD vs MCI

0.48 (0.25–0.90)

0.02*

High Intraocular pressure:

     Dementia vs SCD

0.85 (0.40–1.83)

0.68

     Dementia vs MCI

1.08 (0.69–1.70)

0.73

     SCD vs MCI

1.27 (0.61–2.62)

0.52

Suboptimal OCT image quality:

     Dementia vs SCD

14.95 (2.01–111.03)

0.01*

     Dementia vs MCI

2.01 (1.36–2.98)

<0.001*

     SCD vs MCI

0.14 (0.02–1.00)

0.05

Abnormal OCT findings:

     Dementia vs SCD

1.23 (0.67–2.25)

0.51

     Dementia vs MCI

0.81 (0.61–1.07)

0.13

     SCD vs MCI

0.66 (0.36–1.18)

0.16

Newly detected ophthalmological pathologies:

     Dementia vs MCI

1.23 (0.64–2.38)

0.54

     Dementia vs SCD

1.07 (0.77–1.50)

0.69

     SCD vs MCI

0.87 (0.46–1.66)

0.67

  1. A Multinomial Logistic Regression model including age, gender and years of education as co-variates was used to analyse group differences in ophthalmological exam and OCT scan findings. For each comparison, the first listed group acted as the reference one. Statistical significance was set-up at p < 0.05.
  2. CI = confidence interval; MCI = mild cognitive impairment; OCT = optical coherence tomography; OR = odds ratio; SCD = subjective cognitive decline.
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