Table 3 Overall and region-based detection rate using combined T1 + T2 + DWI sequence MRI evaluation.

From: Accuracy of standard clinical 3T prostate MRI for pelvic lymph node staging: Comparison to 68Ga-PSMA PET-CT

T1 + T2

N

Sensitivity + 95% CI

Specificity + 95% CI

PPV + 95 95% CI

NPV + 95% CI

All LN

146/187

81.6%

(71.1–88.9%)

98.6%

(97.6–99.2%)

73.5%

(52.1–87.6%)

99.5%

(98.8–99.8%)

Iliac left

23/31

80.7%

(60.0–92.1%)

98.5%

(95.8–99.4%)

52.5%

(18.4–84.4%)

99.6%

(98.0–99.9%)

Iliac right

30/47

66.8%

(46.6–82.2%)

97.2%

(93.7–98.8%)

72.5%

(37.8–92.0%)

98.8%

(95.0–99.7%)

Obturator left

28/33

84.9%

(62.8–95.0%)

98.6%

(95.4–99.6%)

85.1%

(39.4–98.0%)

98.3%

(87.1–99.8%)

Obturator right

44/52

88.8%

(75.0–95.5%)

97.1%

(92.7–98.9%)

91.8%

(66.2–98.5%)

96.9%

(84.3–99.4%)

Presacral

13/16

82.0%

(50.0–95.4%)

100%

(100–100%)

99.8%

(0–100%)

95.9%

(0–100%)

Inguinal

8/8

100%

(0–100%)

99.2%

(0–100%)

28.5%

(5.3–73.8%)

100%

(100–100%)

  1. This table summarizes the region-based analysis of the lymph node metastases in MRI using T1 combined with T2 and DWI sequence evaluation. The columns present number, sensitivities, specificities, positive and negative predictive value including 95% confidence interval. The rows are fielded in the six defined anatomical regions iliac left and right, obturator left and right, presacral and inguinal region.
  2. Abbreviations: LN = Lymph nodes, PPV = positive predictive value, NPV = Negative predictive value, CI = 95% Confidence interval.
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