Figure 5 | Scientific Reports

Figure 5

From: Analysis of the 4q35 chromatin organization reveals distinct long-range interactions in patients affected with Facio-Scapulo-Humeral Dystrophy

Figure 5

Expression of genes of the 4q35 region in controls and FSHD biopsies (muscle). Gene expression quantified by RT-qPCR in control (n = 7, Blue); FSHD1 (n = 7, Grey) and FSHD2 (n = 3, Red) muscle biopsies (quadriceps femoris). Each measure represents the average fold-change expression of six independent assays (RT triplicate, technical duplicate) normalized to three housekeeping genes (HKG: HPRT, PPIA and GAPDH; ΔΔCt method). Differences from the control group are represented as boxplots with associated statistical significance (Kruskal-Wallis multiple comparison test; α = 0.05) along with means ± SEM. *p < 0.05; **p < 0.01; ***p < 0.005; ****p < 0.001.

Back to article page