Figure 5 | Scientific Reports

Figure 5

From: Contrasting Roles of Cannabidiol as an Insecticide and Rescuing Agent for Ethanol–induced Death in the Tobacco Hornworm Manduca sexta

Figure 5

CBD increases electrophysiological responses measured in the ventral chain ganglia of M. sexta larvae. (A) A low power microscopic image of a 5th-instar chain ganglion which was micro dissected from the larva, and annotation showing where the stimulating electrode was placed in the ganglion, and where the nerve tube was cut and drawn into the recording electrode. (B) A high power image of a methylene blue-stained ganglion. (C) Representative voltage responses following electrical stimulation of ganglia from the M. sexta fed on AD, AD + 1% EtOH, and AD + 1% EtOH + 1 mM CBD (one-way ANOVA, n = 5, p < 0.05). (D) The slope of the negative voltage response plotted as a function the stimulus intensity to quantify the input-output relationships within each treatment group (one-way ANOVA, n = 5, p < 0.05).

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