Table 3 The Cox regression models trained for BRCA and GBM for all patients and for each specific patient group, with different combinations of covariates. Significant covariates and C-index are listed for each model.

All patients-all covariates

ER status (−0.118)

0.724

age at diagnosis (0.486)

0.665

Her2 status (0.122)

module 1 (−0.496)

age at diagnosis (0.196)

module 4 (0.374)

tumour histology type (−0.226)

module 11 (0.738)

lymph node assessment (0.264)

size of tumour (0.169)

module 2 (0.201)

module 5 (−0.205)

Patient group 1-all covariates

tumour histology type (−0.504)

0.665

age at diagnosis (0.475)

0.684

lymph node assessment (0.687)

module 7 (−0.479)

module 2 (0.450)

module 11 (1.816)

Patient group 2-all covariates

Her2 status (0.335)

0.701

age at diagnosis (0.496)

0.688

age at diagnosis (0.473)

module 2 (0.689)

lymph node assessment (0.179)

module 12 (1.400)

size of tumour (0.455)

module 1 (0.408)

module 2 (0.270)

module 5 (−0.497)

Patient group 3-all covariates

tumour histology type (−0.605)

0.680

age at diagnosis (0.620)

0.624

lymph node assessment (0.354)

Patient group 4-all covariates

ER status (−0.508)

0.717

module 4 (1.079)

0.707

PR status (−0.354)

module 8 (1.796)

age at diagnosis (0.311)

module 9 (−1.066)

lymph node assessment (0.368)

size of tumour (0.118)

module 2 (0.378)

Patient group 5-all covariates

lymph node assessment (0.226)

0.680

age at diagnosis (0.384)

0.759

size of tumour (0.248)

module 1 (−1.840)

module 2 (−1.144)

module 3 (1.862)

module 5 (−1.609)

module 6 (−1.711)

module 11 (2.743)

module 12 (1.343)

Patient group 6-all covariates

NA

age at diagnosis (0.789)

0.720

module 1 (−1.196)

module 5 (1.355)

module 11 (1.666)