Figure 6

CNTN-1 promoted EMT progression via activation of the AKT pathway in resistant cells. (a) p-AKT was up-regulated in H446-BR and H526-BR cells, and down-regulated in the CNTN-1 silenced arms. (b) p-AKT, vimentin, N-cadherin and E-cadherin were tested by Western blot after LY294002 treatment (3 days).