Figure 4 | Scientific Reports

Figure 4

From: Clinical, pathophysiologic, and genomic analysis of the outcomes of primary head and neck malignancy after pulmonary metastasectomy

Figure 4

Network analysis mapped genes with validation via ingenuity pathway analysis (IPA). The genes mapped by DAVID were validated with IPA45. The selected criteria and gene lists are shown in Table S9. (a) The genes from short-term PMS HNSCC only. HSD17B10 was a hub-node gene. Other genes, such as FN1, EP300, CASP8, EGF, and MAP2K1, associated with the pathways involved in cancer, were also identified as hub-node genes. (b) The genes from long-term PMS HNSCC only. (c) The genes from the intersection between short-term PMS HNSCC only and ACC. HSD17B10 was also a hub-node gene in the crossover mutation between these two groups. (d) The genes from the intersection between long-term PMS HNSCC only and ACC.

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