Figure 1 | Scientific Reports

Figure 1

From: Staphylococcal enterotoxins modulate the effector CD4+ T cell response by reshaping the gene expression profile in adults with atopic dermatitis

Figure 1

Staphylococcal enterotoxins drive CD4+ T cells to an anergic profile in AD. (a) Heatmap of the relative expression values of 84 key genes related to T-cell anergy in FACS-sorted CD4+ T cells analyzed by PCR array. The genes were classified according to functional criteria expressed on a thermal scale for HC (n = 3) and AD patients (n = 3) at baseline and after SEA stimulation. Expression of upregulated genes EGR2 (b) and IL13 (c) was confirmed by RT-qPCR (n = 8–9). Bars represent median with interquartile range. *p < 0.05.

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