Figure 3 | Scientific Reports

Figure 3

From: NeTFactor, a framework for identifying transcriptional regulators of gene expression-based biomarkers

Figure 3

Subnetwork of the base nasal GRN consisting of the seven regulator TFs listed in Table 1, and their target asthma biomarker genes, denoted by squares and small filled circles respectively. The most significant regulators of the biomarker, ETV4 and PPARG, and the genes regulated exclusively by each of them are shown in green and pink respectively, and those regulated by both TFs are shown in yellow. Other TFs and target genes are shown in grey, with the exception of ESR1, which is itself regulated by PPARG. Figure made using CytoScape71.

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