Table 3 Comparison of our proposed MPBG biomarkers with state-of-the-art methods based on s-MRI and d-MRI using a similar ADNI2 dataset.

From: Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification

Method

Subjects

Feature

Classifier

Classification ACC

CN

eMCI

lMCI

AD

CN/AD

eMCI/lMCI

Nir et al.93

44

74

39

23

Tractography

SVM

84.9%

n/a

Prasad et al.60

50

74

38

38

Connectivity network

SVM

78.2%

63.4%

Zhan et al.94

n/a

73

39

n/a

Connectivity network

SLG

n/a

65.0%

Maggipinto et al.96

50

22

18

50

Voxel-based

RF

87.0%

n/a

La Rocca et al.95

52

85

38

47

Connectivity network

RF

83.0%

n/a

MPBG hippocampus

62

65

34

38

Patch-based

LDA

88.1%

68.8%

MPBG Subiculum

62

65

34

38

Patch-based

LDA

86.5%

70.8%

  1. All results are expressed in percentage of accuracy.
  2. LDA = Linear Discriminant Analysis,
  3. SLG = Sparse Logistic Regression,
  4. SVM = Support Vector Machine,
  5. RF = Random Forest.