Figure 1
From: SLE Plasma Profiling Identifies Unique Signatures of Lupus Nephritis and Discoid Lupus
Association between established systemic lupus erythematosus (SLE) biomarkers and different SLE pathologies. (a) Area under the curve (AUC) for established SLE biomarkers in all SLE (n = 189) versus healthy donors (HD; n = 26). (b) Spearman’s rank correlation of established SLE biomarkers with SLE Disease Activity Index (SLEDAI) and modified SLEDAI to exclude serological components, C3, and anti–double-stranded DNA (anti-dsDNA) antibody components of score (modified SLEDAI). Dotted lines represent Spearman’s R critical values needed to achieve statistical significance with α = 0.05. (c) AUC of established biomarkers compared between plasma samples drawn from patients with SLE with different manifestations. ACL = acute cutaneous lupus; CL = cutaneous lupus; DL = discoid lupus; Ig = immunoglobulin; LN = lupus nephritis; SS = Sjögren’s syndrome.
