Figure 1 | Scientific Reports

Figure 1

From: RETRACTED ARTICLE: Chondro-protective effects of polydatin in osteoarthritis through its effect on restoring dysregulated autophagy via modulating MAPK, and PI3K/Akt signaling pathways

Figure 1

Chondro-protective effects of PD on IL-1β-induced chondrocytes. (A) Chemical structures of PD. MTT assay was applied to detect the cytotoxicity of PD on chondrocytes with (C) or without (B) IL-1β. Values are the means ± SD (**p < 0.01, ***p < 0.001 indicate the significant difference amount the experiments, n = 5). After cultured with IL-1β, PD and 3-MA for 24 h, cell proliferation was determined by MTT assay (D). Values are the means ± SD (n = 5). Bars with different letters are significantly different from each other atp < 0.05 and those with the same letter exhibit no significant difference. Meanwhile, (E) H&E, (F) Saf-O and (G) FDA/PI staining of chondrocytes were applied for cell morphology, GAG production, and viability. Original magnification × 200 (scale bar, 300 μm).

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