Figure 8 | Scientific Reports

Figure 8

From: Microbial metabolite deoxycholic acid controls Clostridium perfringens-induced chicken necrotic enteritis through attenuating inflammatory cyclooxygenase signaling

Figure 8

Aspirin attenuates NE-induced intestinal inflammation and apoptosis. Cohorts of thirteen chickens were fed basal and 0.12 g/kg aspirin diet. The birds were infected as in Fig. 2 and four birds per group were sampled at 26 days of age. (A) H&E staining showing representative intestinal histology images. (B) Quantification of histological intestinal damage score. (C) Representative cell apoptosis (green) using TUNEL assay. (D) Quantification of apoptotic cells. Scale bars are 200 μm in panel A and 10 μm in panel C. NE + ASP, NE birds fed aspirin diet. All graphs depict mean ± SEM. *P < 0.05; ***P < 0.001. Results are representative of 2 independent experiments.

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