Figure 1 | Scientific Reports

Figure 1

From: Loss of the dermis zinc transporter ZIP13 promotes the mildness of fibrosarcoma by inhibiting autophagy

Figure 1

ZIP13 is downregulated in fibrosarcoma. (a) Real-time PCR analysis reveals that ZIP13 is one of the predominant zinc transporter transcripts in normal human fibroblasts. The data represent three independent experiments. (b) Real-time PCR analysis reveals that ZIP13 is downregulated in the HT1080 fibrosarcoma cell line. The data are presented as mean ± SD of three independent experiments (***P < 0.005). (c) Real-time PCR analysis reveals that ZIP13 is downregulated in different cancer cell lines compared to placental cDNA. The data represent three independent experiments. (d) Real-time PCR analysis reveals that 5 μM 5-aza-2′-deoxycytidine (5-Aza) treatment increases ZIP13 expression in the HT1080 fibrosarcoma cell line. The data are presented as mean ± SD of three independent experiments (*P < 0.05, **P < 0.01).

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