Figure 1 | Scientific Reports

Figure 1

From: Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection

Figure 1

Effects of ion channel inhibitor combinations on densities of Iba1+ and ED1+ cells. Densities of Iba1+ (A), ED1+ (B) and Iba1+/ED1+ (C) cells in the ventral optic nerve from uninjured normal; sham injured, local vehicle treated animals; injured, systemic and local vehicle treated animals; and systemic and local ion channel inhibitor treated animals 3 days after partial optic nerve transection. N = 8–10 rats per group; graphs display min to max values, with the central line representing the median data point. Significant differences are indicated by *p ≤ 0.05. (D) Representative images of Iba1+, ED1+ and Iba1+/ED1+ cells, indicated with arrow heads; scale bars = 10 µm.

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