Figure 2 | Scientific Reports

Figure 2

From: Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection

Figure 2

Effects of injury and ion channel inhibitor combinations on the plasma concentration of cytokine and chemokine analytes. Concentration of MIP-2 (A), IP-10 (B), RANTES (C), MIP-1α (D), MCP-3 (E), MCP-1 (F), and Eotaxin (G) in the plasma of uninjured normal; sham injured, local vehicle treated animals; injured, systemic and local vehicle treated animals; and systemic and local ion channel inhibitor treated animals 3 days after partial optic nerve transection. Graphs display min to max values, with the central line representing the median data point; N = 5–6 rats per group. Significant differences indicated by *p ≤ 0.05 and ***p ≤ 0.001.

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