Figure 3 | Scientific Reports

Figure 3

From: Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection

Figure 3

Effects of ion channel inhibitor combinations on oligodendroglial cells. Densities of Olig2+ oligodendroglial cells (A) and PDGFαR+/Olig2+ OPCs (C) in the ventral optic nerve from uninjured normal; sham injured, local vehicle treated animals; injured, systemic and local vehicle treated animals; and systemic and local ion channel inhibitor treated animals 3 days after partial optic nerve transection. N = 8–10 rats per group. Graphs display min to max values, with the central line representing the median data point. Representative image of Olig2+ cells (B) and OPCs (D), indicated with arrow heads; scale bars = 10 µm.

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