Figure 5 | Scientific Reports

Figure 5

From: Targeting ERβ in Macrophage Reduces Crown-like Structures in Adipose Tissue by Inhibiting Osteopontin and HIF-1α

Figure 5

Decrease in CLS number in both SAT and VAT of WD-induced obese mice by LY3201 treatment. (A) Iba1 staining in SAT and VAT. In vehicle-treated mice, there were many CLS in both SAT and VAT (a,b). There were much less CLS in both SAT and VAT of LY3201-treated mice (c,d). (B,C) LY3201 treatment significantly decreased CLS number in both SAT and VAT (*P < 0.01). For each picture, a close-up view of a CLS has been included. (Scale bars in A, 500 μm).

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