Figure 7 | Scientific Reports

Figure 7

From: Targeting ERβ in Macrophage Reduces Crown-like Structures in Adipose Tissue by Inhibiting Osteopontin and HIF-1α

Figure 7

Decrease in HIF-1α expression and nuclear translocation in macrophages upon treatment with LY3201. There was strong HIF-1α expression in both cytoplasm and nuclei in macrophages of the vehicle-treated mice (red arrows) (a,b). LY3201 downregulated HIF-1α cytoplasm expression and obviously decreased nuclear HIF-1α (c,d). For each picture, a close-up view has been included. (Scale bars in a–d, 50 μm).

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