Table 2 Baseline Clinical Characteristics According to PKD Genotypes.
Variables | Total | PKD1-PT | PKD1-ID | PKD1-NT | PKD 2 | P value | |
|---|---|---|---|---|---|---|---|
N (%) | 630 | 371 (59.0) | 21 (3.0) | 119 (19.0) | 119 (19.0) | Â | |
Male, n (%) | 304 (48.3) | 175 (47.2) | 12 (57.1) | 68 (57.1) | 49 (41.2) | 0.975 | |
Age, [mean ± SD] | 45.6 ± 12.9 | 44.2 ± 12.9 | 45.0 ± 10.6 | 43.3 ± 12.6 | 48.9 ± 13.0 | 0.001 | |
1st visit age, 569, [mean ± SD] | 41.9 ± 12.9 | 40.2 ± 12.9 | 39.8 ± 10.0 | 43.3 ± 12.6 | 45.9 ± 13.0 | <0.001 | |
Hypertension, 590, n (%) | 451 (71.6) | 266 (71.7) | 16 (80.0) | 88 (77.2) | 81 (75.7) | 0.969 | |
Hypertension Dx age, 316, [mean ± SD] | 38.8 ± 10.0 | 37.3 ± 10.1 | 38.6 ± 7.4 | 39.0 ± 8.9 | 43.4 ± 10.5 | <0.001 | |
ESRD | 122 (19.4) | 84 (22.6) | 4 (19.0) | 22 (18.5) | 12 (10.1) | 0.004 | |
Median age of ESRD | 53.6 | 63.5 | 72.7 | 68.8 | 72.9 | <0.001 | |
Death | 23 (3.7) | 13 (3.5) | 1 (4.8) | 5 (4.2) | 4 (3.4) | 0.908 | |
Death age, 23, [mean ± SD] | 62.8 ± 13.8 | 61.4 ± 16.2 | 63.4 | 63.9 ± 9.1 | 65.7 ± 14.6 | 0.745 | |
htTKV, median [IQR] | 781 [432, 1356] | 898 [476, 1546] | 901 [544, 1271] | 609 [397, 1179] | 629 [373, 1160] | <0.001 | |
eGFR by CKD-EPI, 620, [mean ± SD] | 65.9 ± 40.0 | 63.5 ± 42.2 | 64.7 ± 38.3 | 66.6 ± 37.8 | 73.1 ± 33.8 | 0.052 | |
*Grade, [n(%)] | 1A | 44 (7.0) | 18 (4.9) | 1 (4.8) | 14 (11.8) | 11 (9.2) | <0.001 |
1B | 158 (25.1) | 70 (18.9) | 2 (9.5) | 35 (29.4) | 51 (42.9) | ||
1C | 206 (32.7) | 127 (34.2) | 11 (52.4) | 36 (30.3) | 32 (26.9) | ||
1D | 153 (24.3) | 99 (26.7) | 7 (33.3) | 25 (21) | 22 (18.5) | ||
1E | 69 (11.0) | 57 (15.4) | 0 (0) | 9 (7.6) | 3 (2.5) | ||
