Figure 3 | Scientific Reports

Figure 3

From: Humoral Immunogenicity and Efficacy of a Single Dose of ChAdOx1 MERS Vaccine Candidate in Dromedary Camels

Figure 3

Severity and abundance of nasal discharge post natural infection challenge. The twenty camels in all groups (−C, −V, +C, and +V) were challenged with ten naturally infectious camels; and nasal discharges were assessed for their abundance and severity for 14 d.p.c.; using arbitrary units of 0 (N: normal), 0.25 (R: recovered), 1 (+: mild), 2 (++: moderate), or 3 (+++: severe). (A) Representative photos taken from different camels in different days. (B) Areas under the curve (AUC) for the nasal discharge scores collected daily from 1 to 14 d.p.c. are plotted. The analysis of mixed model on AUC of nasal discharge scores and fixed factors (d.p.c., seropositivity, and vaccine) shows that the overall vaccine effect over time was significant, p = 0.0274.; also +V had statistically significantly lower scores as compared to +C, by Kruskal-Wallis test with Dunn’s Multiple comparison test. d.p.i.: days post immunisation. +: Seropositive; −: seronegative; (C) control group; V: vaccinated group.

Back to article page