Figure 3 | Scientific Reports

Figure 3

From: Upregulation of Yy1 Suppresses Dilated Cardiomyopathy caused by Ttn insufficiency

Figure 3

Upregulation of Yy1 modulates cardiac structural contractile, cell proliferation and survival related gene expression. (A) Heat map representing color-coded expression level of 134 genes that significantly changed in Yy1 treated group (Ttn shRNA + Yy1) in comparison to Ttn shRNA group (Ttn shRNA + EGFP). Virus does, 0.2E + 13 vg/kg. Mice were harvest four weeks after transduction, n ≥ 3. (B) Top10 gene sets of GO of each category by GSEA, arranged by −log P value. (C) Quantitative real-time PCR analysis of Ankrd23, Fhl1, Abra expression in control, Ttn shRNA and Yy1 treated group, n ≥ 3.

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