Table 4 Factors affecting cognitive impairment after sedation using linear regression analysis.
Variable | Univariable | Multivariable | ||
|---|---|---|---|---|
B (SE) | P value | B (SE) | P value | |
Age | 4.29 (1.12) | <0.001 | 4.20 (0.91) | <0.001 |
Sex | ||||
    Female | 1 (Ref) |  |  |  |
    Male | 1.33 (31.16) | 0.966 |  |  |
ASA class | ||||
    I | 1 (Ref) |  | 1 (Ref) |  |
    II | 72.97 (23.15) | 0.003 | 32.06 (17.43) | 0.071 |
Education level | ||||
    High-educated (≥9 years) | 1 (Ref) |  | 1 (Ref) |  |
    Low-educated (<9 years) | 118.20 (27.02) | <0.001 | 85.17 (20.99) | <0.001 |
Etiology | ||||
    Non-alcohol | 1 (Ref) |  |  |  |
    Alcohol | 28.46 (24.87) | 0.257 |  |  |
Ascites | ||||
    None | 1 (Ref) |  | 1 (Ref) |  |
    Mild to moderate | 62.43 (26.81) | 0.023 | −8.17 (21.13) | 0.700 |
    Severe | 83.10 (29.88) | 0.007 | 31.57 (22.24) | 0.162 |
MELD score | 7.53 (2.34) | 0.002 | 7.59 (1.84) | <0.001 |
Esophageal varices | ||||
      No | 1 (Ref) |  |  |  |
      F1 | 30.97 (38.04) | 0.419 |  |  |
      F2 | 35.73 (36.23) | 0.328 |  |  |
      F3 | 33.85 (53.33) | 0.528 |  |  |
Gastric varices | ||||
    No | 1 (Ref) |  |  |  |
    Present | −12.97 (30.21) | 0.669 |  |  |
Sedative drug | ||||
    Midazolam only | 1 (Ref) |  |  |  |
    Propofol only | −3.61 (30.52) | 0.906 |  |  |
    Midazolam + Propofol | 25.07 (0.52) | 0.415 |  |  |
