Table 1 Baseline characteristics before and after propensity score matching.

From: Rituximab protects against development of atherosclerotic cardiovascular disease after kidney transplantation: a propensity-matched study

Variables

Before matching

After matching

Rituximab (n = 245)

Control (n = 1054)

P

Rituximab (n = 239)

Control (n = 401)

P

Age (years)

46.1 ± 10.5

45.1 ± 11.5

0.210

46.0 ± 10.6

44.6 ± 12.2

0.144

Sex, males

116 (47.3%)

645 (61.2%)

<0.001

115 (48.1%)

207 (51.6%)

0.391

Body mass index (kg/m2)

22.3 ± 3.4

22.5 ± 3.3

0.298

22.3 ± 3.4

22.3 ± 3.5

0.754

Deceased donor

20 (8.2%)

334 (31.7%)

<0.001

20 (8.4%)

40 (10.0%)

0.500

Dialysis duration (months)

4 (27)

13 (73)

<0.001

4 (28)

5 (28)

0.429

Retransplantation

39 (15.9%)

87 (8.3%)

<0.001

33 (13.8%)

38 (9.5%)

0.091

Use of tacrolimus (vs. cyclosporin)

237 (96.7%)

776 (73.6%)

<0.001

231 (96.7%)

384 (95.8%)

0.573

Pretrasnplant alcohol use

47 (19.2%)

184 (17.5%)

0.524

47 (19.7%)

61 (15.2%)

0.146

Pretransplant smoking

47 (19.2%)

215 (20.4%)

0.669

47 (19.7%)

77 (19.2%)

0.886

Pretransplant DM

71 (29.0%)

193 (18.3%)

<0.001

66 (27.6%)

105 (26.2%)

0.692

Pretransplant ASCVD history

19 (7.8%)

71 (6.7%)

0.572

18 (7.5%)

31 (7.7%)

0.927

SBP ≥ 140 mm Hg

111 (50.9%)

568 (57.5%)

0.074

109 (51.4%)

214 (56.3%)

0.251

DBP ≥ 90 mm Hg

84 (38.7%)

436 (44.2%)

0.138

83 (39.3%)

168 (44.3%)

0.240

Total cholesterol ≥ 240 (mg/dL)

6 (2.4%)

30 (2.8%)

0.733

6 (2.5%)

8 (2.0%)

0.666

LDL cholesterol ≥ 100 (mg/dL)

39 (15.9%)

323 (30.7%)

<0.001

39 (16.3%)

76 (19.0%)

0.401

Use of statin

51 (20.8%)

214 (20.3%)

0.858

48 (20.1%)

90 (22.4%)

0.482

Biopsy-proven acute rejection within 1 year

64 (26.1%)

130 (12.3%)

<0.001

62 (25.9%)

41 (10.2%)

<0.001

eGFRa at 1 month (mL/min)

66.4 ± 24.6

62.9 ± 21.3

0.042

65.7 ± 24.3

65.1 ± 20.6

0.715

  1. aCalculated using Chronic Kidney Disease Epidemiology (CKD-EPI) formula.
  2. ASCVD, atherosclerotic cardiovascular disease; DBP, diastolic blood pressure; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; KT, kidney transplantation; LDL, low density lipoprotein; SBP, systolic blood pressure.