Table 2 Final population pharmacokinetic model estimates (Abbreviation: RSE: residuals standard error).
From: Pharmacokinetics of Micafungin in Critically Ill Patients
Parameter | Empirical Bayes Estimate | RSE (%) |
|---|---|---|
Clearance [L/h] | 1.56 | 4.8 |
Central volume of distribution (L) | 16.2 | 12.7 |
Inter-compartmental clearance [L/h] | 14.4 | 7.7 |
Peripheral volume of distribution [L] | 13.8 | 15.7 |
Proportional residual Error (%) | 0.257 | 7.4 |
Inter-individual Variability Clearance (%) | 25.9 | 9.8 |
Inter-individual Variability Peripheral volume of distribution (%) | 70 | 13 |
Inter-individual Variability Central volume of distribution (%) | 48.9 | 13.4 |
