Figure 4 | Scientific Reports

Figure 4

From: Partial reduced Pi transport function of PiT-2 might not be sufficient to induce brain calcification of idiopathic basal ganglia calcification

Figure 4

PiT-2 membrane translocation was present in PiT-2 missense variants by HiBiT Extracellular System. (a) Schematic of the HiBiT Extracellular System. (b) Measurement of the membrane translocation rate using the HiBiT Extracellular System. Data were normalized to the mock-transfected cells and corrected to PiT-2-WT representing 1. Each value represents the mean ± SEM of three determinations, relative to the Naive. The significance of any difference was determined using ANOVA, followed by the Bonferroni/Dunn post hoc test (†p < 0.05 versus WT).

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