Table 3 Expression status of molecular markers in LGG and HGG.
From: Intratumoral Susceptibility Signals Reflect Biomarker Status in Gliomas
Characteristics | ITSS grade | |||||
|---|---|---|---|---|---|---|
ITSS 0 | ITSS 1 | ITSS 2 | ITSS 3 | Total | P-valuea | |
LGG | ||||||
IDH1 status | Â | Â | Â | Â | Â | >0.99 |
Mutant | 3 | 32 | 6 | 2 | 43 | Â |
Wild-type | 0 | 3 | 1 | 0 | 4 | Â |
MGMT status | Â | Â | Â | Â | Â | >0.99 |
Methylation | 7 | 37 | 7 | 2 | 53 | Â |
Non-methylation | 0 | 1 | 0 | 0 | 1 | Â |
1p19q status | Â | Â | Â | Â | Â | 0.206 |
Codeletion | 2 | 15 | 5 | 1 | 23 | Â |
Non-codeletion | 5 | 19 | 3 | 1 | 28 | Â |
HGG | ||||||
IDH1 status | Â | Â | Â | Â | Â | <0.01 |
Mutant | 2 | 5 | 3 | 8 | 18 | Â |
Wild-type | 0 | 2 | 0 | 18 | 20 | Â |
MGMT status | Â | Â | Â | Â | Â | 0.041 |
Methylation | 2 | 6 | 4 | 17 | 29 | Â |
Non-methylation | 0 | 2 | 0 | 16 | 18 | Â |
1p19q status | Â | Â | Â | Â | Â | 0.273 |
Codeletion | 0 | 4 | 0 | 3 | 7 | Â |
Non-codeletion | 2 | 5 | 4 | 19 | 30 | Â |
