Figure 2
Comparison of lesion thickness and density of immune infiltrate with lesion diagnosis. Lesion thickness and immune cell infiltrate scores were determined as outlined in Fig. 1 and compared against lesion diagnosis. (a) Lesion thickness vs. Lesion type. (b) Infiltration score vs. Lesion subtype. One-way ANOVA with post-hoc Tukey’s multiple comparisons test. (c) Heat map color corresponds to the Log-transformed concentrations. The spectrum of black to purple to orange to yellow corresponds to increasing gradient of chemokine/cytokine concentrations. Unsupervised hierarchical clustering was performed across samples (columns) and cytokines/chemokines abundance (rows) and are ordered according to similarity of the expression profile by samples. Normal = peritumoural skin.
