Figure 1

Elevated plasma levels of chemokines in PTB individuals (A) The plasma levels of chemokines were measured in PTB (n = 88), LTB (n = 44) and HC (n = 44) individuals. The data are represented as scatter plots with each circle representing a single individual. P values were calculated using the Kruskal-Wallis test with Dunn’s post hoc comparison. (B) PCA (Principle component analysis) plot computing normalized ELISA data from baseline plasma levels of cytokines in combination of two different experimental groups first PTB (Colored in blue) vs LTB (Colored in red) and second PTB (Colored in blue) vs HC (Colored in red). (C) ROC analysis to estimate the sensitivity, specificity and AUC was performed using chemokines to estimate the capacity of these factors to distinguish individuals with PTB vs. LTB.