Figure 7
From: Improving the odds of drug development success through human genomics: modelling study
Study designs relevant to drug target identification and validation based on human genomics: (a) conventional genome-wide association analysis in which variation in 20,000 genes is tested against a single disease; (b) phenome wide association analysis of a gene encoding a drug target in which variation in a single druggable gene is evaluated against many (all) diseases; (c) druggable genome and phenome wide association analysis; and (d) whole genome and phenome wide association analysis.
