Figure 1
From: Nano-encapsulated Escherichia coli Divisome Anchor ZipA, and in Complex with FtsZ
The schematic representation of SMALP-ZipA and SMALP-ZipA:FtsZ. (A) The chemical structure of SMA co-polymer which has a ratio of 2:1 styrene to maleic acid (adapted from Lee et al.)39. (B) Schematic representation of SMALP-ZipA (created using BioRender.com) 1TMH is encapsulated in native lipid (grey) from the E. coli membrane, and surrounded by an SMA disc (red). ZipA (pink) shows the first 6 amino acids exposed on the periplasmic side of the membrane, aa 7–28 form a 1TMH, 29–85 aa lead into the cytoplasmic region of the cell, and are connected by a flexible linker, the PQ ___domain, to the globular ___domain (GD) consisting of 186–328 aa. (C) Schematic representation of the SMALP-ZipA:FtsZ complex.
