Figure 3
From: Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p
The effects of miR-339-5p and paeonol on LPS-induced RAW264.7 cells at the 12-h and 24-h time points, as measured by Western blotting. (A–D) Analysis of the levels of the inflammation-related proteins HMGB1, TNF-α and IL-1β in the (1) normal control, (2) LPS, (3) LPS + miR-339-5p mimic, (4) LPS + miR-339-5p inhibitor and (5) LPS + Paeonol groups of LPS-induced RAW264.7 cells by Western blotting. Note: **P < 0.01 and ***P < 0.001 in comparison with the control group; ▲▲P < 0.01 and ▲▲▲P < 0.001 in comparison with the model group (LPS); #P < 0.05.
