Figure 1

Intestinal pathogenic burdens over time following murine fecal microbiota transplantation of C. jejuni infected secondary abiotic mice. Secondary abiotic mice were infected with C. jejuni on days 0 and 1 by gavage. Starting a week later, infected mice were subjected to peroral fecal microbiota transplantation (FMT; Day (D) 0) from murine donors (open circles) on three consecutive days or received vehicle (mock; closed circles). Before and after FMT, C. jejuni loads were determined in fecal samples taken at indicated time points by culture and expressed as colony forming units per gram (CFU/g). Medians, numbers of culture-positive mice out of the total numbers of analyzed animals (in parentheses) and significance levels (p-values; **p < 0.01; ***p < 0.001) determined by the Mann-Whitney U test are given. Data were pooled from three independent experiments.