Table 3 SNPs associated with NVS phenotype in the EPOS series (n = 1494).

From: Identification of genetic polymorphisms modulating nausea and vomiting in two series of opioid-treated cancer patients

Chromosome

SNP

Position (Mb)*

Gene

Minor allele

Beta§

P value§

1

rs36024412

26.344

AIM1L

T

−2.172

0.042

1

rs168107

108.937

CLCC1

T

−3.545

0.001

6

rs41269255

27.309

POM121L2

T

3.299

0.025

6

rs9393888

28.091

ZNF165

C

−3.071

0.011

12

rs12305038

20.369

PDE3A

A

−3.325

0.002

19

rs11882256

8.950

MUC16

T

2.791

0.016

  1. NVS, nausea-vomiting score.
  2. *Map position, in megabases, based on genome assembly GRCh38.p12.
  3. §PLINK, linear regression model of allelic effects on phenotype; covariates: sex, age, country of residence, and opioid type (see Table 1).
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