Figure 3

Fusion transcripts identified in single cells from adult human brain. (a) Circos plot represents 911 unique fusions and signifies 82% (749/911) of the identified events are Inter-chromosomal. Here, periphery of the plot represents different chromosomes and links denote fusion events. Red links are inter-chromosomal event involving genes from two different chromosomes and links that are in green are intra-chromosomal fusion between genes from same chromosome. (b) Neurons (blue) harbor significantly higher number of fusions compared to astrocytes (red) (one tailed Wilcoxon p value < 10−3 marked by **), where boxplot represents number of fusion transcripts identified in each cell. Horizontal axis denotes brain cells while vertical axis represents number of fusion transcripts normalized with total data generated in that cell.