Figure 2

Differentiation of subtypes. (A) Heatmap of DGM, ESR1, PgR, HER2, and MKI67 gene expression levels in all 752 patients (X-axis for PAM50 subtypes); Unsupervised clustering DGM genes, ESR1, PgR, HER2 and MKI67 (Y-axis); (B) DGM score distribution according to PAM50 subtypes and ROR scores. The X-axis for ROR score; Y-axis for DGM score. PAM50 subtypes: Orange dots represent the basal-like subtype, grey dots the HER2 subtype, green dotes luminal A, blue dots luminal B, and pink dots represent the normal type; (C) C-indices for all subtypes; (D) C-indices for N0 luminal subtype (ER/PR+ and HER2−) patients only.