Figure 5

hESCs-mediated collagen I gel contraction after 7 days in response to oxytocin (10 nM). (A) control sample without oxytocin (B) control sample with oxytocin, (C) gel containing strained cells without oxytocin, and (D) gel containing strained cells with oxytocin. (E) The graph represents the gel area 7 days after release normalized to the initial area. The bars represent the mean ± standard error of gel area (n = 4) (p-value was obtained from ANOVA followed by Fisher’s LSD; *p < 0.05, **p < 0.005; the statistical analysis was performed using the original area measurement data).