Table 1 Analysis of Babesia microti antigenic proteins.
GeneID* | Accession | Curated Domain Architecture | Function | Comments |
---|---|---|---|---|
BmR1_03g00785 | XP_012648767.1 | SIG + BAHCS1 | adhesion/Cell surface/exported protein |  |
BmR1_04g08155 | XP_012650223.1 | SIG + Bm-SERA1 | adhesion/Cell surface/exported protein |  |
BmR1_02g04285 | XP_012648612.1 | SIG + BmMCFRP1 /MN15/BMN1–15 Maltese cross form related protein | adhesion/Cell surface/exported protein |  |
BmR1_03g04855 | XP_012649578.1 | SIG + PiβS1 ___domain | adhesion/Cell surface/exported protein |  |
BmR1_03g00690 | XP_012648749.1 | SIG + EGF + EGF + EGF + EGF | adhesion/Cell surface/exported protein |  |
BmR1_01g03455 | XP_012647758.1 | AP2 DNA-binding ___domain | Transcription | AP2 |
BmR1_02g00670 | XP_012647909.2 | TP + peptidylprolyl isomerase | Plastid protein folding protein | peptidylprolyl isomerase with a transit peptide |
BmR1_03g03490 | XP_012649309.1 | sGTPase | Translation | elongation factor EF-1 alpha subunit |
BmR1_04g06300 | XP_012649865.1 | SIG | adhesion/Cell surface/exported protein | Â |
BmR1_01g01121 | XP_012647300.2 | Apicomplexa specific ___domain (173–231) | Miscellaneous | Apicomplexan+Vitrella |
BmR1_04g08775 | XP_012650340.1 | HSP90 | Chaperone | HSP90 |
BmR1_02g02760 | XP_012648315.1 | NTN-HYDROLASE | protein degradation | 20 S proteasomal Peptidase subunit |
BmR1_03g00420 | XP_012648695.1 | Histone Fold | Chromatin | histone H2A |
BmR1_01g01620 | XP_012647389.1 | PPR repeats | RNA binding and processing | Â |
BmR1_04g09905 | XP_012650554.2 | alpha-helical protein | Miscellaneous | Apicomplexan+Vitrella-specific |
BmR1_02g02985 | XP_012648359.1 | BLBD (Biotin Lipid Binding ___domain)+E3_binding+dehydrogenase | Metabolism | Â |
BmR1_02g03700 | XP_012648499.1 | Acetyltransferase | Chromatin | Histone acetyltransferase 1 |
BmR1_04g07910 | XP_012650176.1 | ubiquitin+UBA | Ubiquitin | Â |
BmR1_02g03965 | XP_012648551.1 | RNA-Helicase | RNA binding and processing | RNA-Helicase |
BmR1_03g00020 | XP_012648615.2 | SIG + PißS ___domain | adhesion/Cell surface/exported protein |  |
BmR1_04g07535 | XP_012650105.1 | SIG + BmMCFRP /MN15/BMN1–15 Maltese cross form related protein | adhesion/Cell surface/exported protein |  |
BmR1_02g00205 | XP_012647816.1 | SIG | adhesion/Cell surface/exported protein | Â |
BmR1_01g01845 | XP_012647436.1 | HAD phosphatase | Miscellaneous | Ortholog of Plasmodium HAD ___domain ookinete protein |
BmR1_03g04120 | XP_012649435.1 | No Hit | Miscellaneous | Â |
BmR1_02g02345 | XP_012648236.1 | Pfimp2 | Miscellaneous | Ortholog of Plasmodium Pfimp2 inner membrane proteins |
BmR1_03g02795 | XP_012649170.1 | Babesia/Theileria specific ___domain | Miscellaneous | Â |
BmR1_03g02390 | XP_012649089.1 | Actin | Cytoskeleton | Actin |
BmR1_04g05965 | XP_012649799.1 | Enolase_N + Enolase_C | Metabolism | Enolase |
BmR1_02g01625 | XP_012648094.1 | GDI (Rossmann fold) | Signaling | Rab GDP dissociation inhibitor beta |
BmR1_04g08040 | XP_012650201.1 | HSP70 | Chaperone | Hsp70 |
BmR1_04g06288 | XP_012649864.1 | Nudix | Metabolism | Nucleotide NDP-X processing |
BmR1_01g02215 | XP_012647511.1 | Pep3/Vps18/deep orange family | Golgi/Vacuolar sorting | Â |
BmR1_01g02270 | XP_012647522.1 | No Hit | Miscellaneous | Â |
BmR1_03g03070 | XP_012649225.1 | Ribosomal_L27A | Ribosomal Protein | large subunit ribosomal protein L27Ae |
BmR1_03g02570 | XP_012649124.1 | SF-assemblin | Cytoskeleton | SF-assemblin/beta giardin |
BmR1_03g04301 | XP_012649471.1 | UFD1 | Ubiquitin | Ubiquitin fusion degradation protein UFD1 |
BmR1_02g00430 | XP_012647861.1 | Utp11 | RNA binding and processing | UTP11 U3 small nucleolar RNA-associated protein 11 |
BmR1_03g02185 | XP_012649047.1 | BBOX | Ubiquitin | Â |
BmR1_03g03720 | XP_012649355.1 | Myosin-ATPase+BZIP + BetaPropeller | Cytoskeleton |  |
BmR1_02g02765 | XP_012648316.1 | Zn-binding ___domain | Miscellaneous | Â |
BmR1_04g07165 | XP_012650036.1 | MIT + AAA + Vps4_C | Cytoskeleton |  |
BmR1_01g03115 | XP_012647688.1 | cNMP_binding+cNMP_binding | Signaling | Â |
BmR1_03g02831 | XP_012649178.2 | Protein kinase | Signaling | Â |
BmR1_01g02860 | XP_012647635.1 | DDRP-beta | DNA replication/processing | DNA-directed RNA polymerase II subunit B |
BmR1_03g02705 | XP_012649152.1 | N-OB + wHTH | DNA replication/processing | Replication A32 |
BmR1_03g02396 | XP_012649091.1 | IWS1 | Chromatin | Â |
BmR1_03g01440 | XP_012648898.1 | RNA-Helicase | RNA binding and processing | inactive RNA helicase |
BmR1_04g05525 | XP_012649711.1 | Peptidase_M24 + METPEPTIDASE-HTH | Miscellaneous | Metallopeptidase |
BmR1_01g01485 | XP_012647367.1 | RNA-Helicase | RNA binding and processing | RNA-Helicase |
BmR1_03g00861 | XP_012648784.1 | sGTPase | Signaling | Â |
BmR1_02g02755 | XP_012648314.1 | sGTPase | Signaling | Â |
BmR1_01g01670 | XP_012647399.1 | SIG + Thioredoxin+Thioredoxin_6+Thioredoxin | Surface/exported protein | ER lumen disulfide bond isomerase |
BmR1_03g02230 | XP_012649056.1 | GOLD | Golgi/Vacuolar sorting | Â |
BmR1_04g09097 | XP_012650403.1 | Sec. 61_beta | secretion | Â |
BmR1_02g03525 | XP_012648466.1 | TM + TM + TM + TM + TM + TM + TM + TM + TM + TM + TM | Surface/exported protein |  |
BmR1_04g09955 | XP_012650565.1 | Cpn60_TCP1 | Chaperone | Â |