Figure 3

Gene expression data from primary human proximal and distal EpCAM+/ALDH− and EpCAM+/ALDH+ cell populations. (A) Principle component (PC) plot of the first three PCs from human TE mRNA-seq samples. Each dot belongs to a population indicated by the dot’s color. The dot’s shape corresponds to the individual that donated the corresponding sample’s Fallopian tube fragment. (B) Bar plots indicating the significance of the association between the indicated PC and the covariate listed on the y-axis. The x-axis corresponds to the statistical significance of the association for each factor on the y-axis and the PC indicated by the title of each subplot. The red line corresponds to a p-value of 0.05. Bars that meet or pass to the right of the red line have a p-value less than 0.05. (C) Differentially expressed genes in human TE populations. Each MA and volcano plot pair displays genes which are differentially expressed between the cell populations indicated in the MA plot’s legend. (D) Heatmap summarizing sample segregation by, and expression of differentially expressed genes. Colors at the top of each column indicate which population the column belongs to. Each row corresponds to a gene found to be differentially expressed in at least one comparison. The colors along each row indicate which population(s) the gene in that row is differentially expressed in.